Flipping the kill switch: How a steroid hormone triggers cellular cannibalism
A study from IISER Kolkata reveals how the steroid hormone ecdysone reprograms epithelial cells into non-professional phagocytes during Drosophila oogenesis.
Research Highlights
For the award-winning papers of ISA
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Rice plants’ resistance movement against increased salinity lies in their own “spools.”
A study from NCBS, Bengaluru, identifies a rice-specific histone variant, H4.V, that acts as a gatekeeper enabling salt-stress tolerance in Oryza.
A tale of two proteins: How an ancient molecular switch balances precision and plasticity in the cell
A study from CSIR-CCMB, Hyderabad, reveals how a single amino acid and a shielding zinc ion decide whether an aaRS favours absolute fidelity or stress-adaptive mistranslation.
Severe dengue: Helper T cells in the spotlight
A study from AIIMS New Delhi identifies a distinct CXCR5⁻ PD-1⁺ CD4⁺ T cell subset that drives B-cell responses and correlates with severe dengue.
How cells navigate their healing journey
A study from TIFR Hyderabad reveals how ER shape helps cells read wound-edge geometry and choose between crawling and contractile closure.
Termite farmers have a weed problem, and a clever fix
A study from IISER Mohali shows how termite farmers detect, isolate, and suppress invasive fungal weeds using microbe-rich soil boluses.
Metabolic redox states reshape mitochondrial organization
A study from inStem, Bengaluru, reveals how redox states and ROS rapidly fragment or reconnect mitochondrial networks independent of mitochondrial activity.
Capsular myofibroblasts form a specialized niche for hematopoietic stem cells in the spleen
A study from IISER Thiruvananthapuram identifies capsular myofibroblasts as a splenic niche that maintains hematopoietic stem cells outside the bone marrow—with implications for extramedullary hematopoiesis and stem-cell therapies.
A star in the ‘DARC’: The unique Duffy antigen receptor for chemokines
This article highlights research in the paper that won the Inspiring Science Awards 2025. The winner is Dr. Shirsha Saha, the first author of the paper.
Disrupting key protein interactions to counter chemoresistance in cancer
This article highlights research in the paper by one of the finalists of the Inspiring Science Awards 2025. The finalist is Ritu Agrawal, also one of the first authors of the paper.
Metabolic switch: New evidence in hematopoiesis
This article highlights research in the paper by one of the finalists of the Inspiring Science Awards 2025. The finalist is Anu P V, also the first author of the paper.
No protein left behind: The ubiquitous formation of cellular condensates
This article highlights research in the paper by one of the finalists of the Inspiring Science Awards 2025. The finalist is Manisha Poudyal, also the first author of the paper
Not all amino acids are treated equally
This article highlights research in the paper by one of the finalists of the Inspiring Science Awards 2025. The finalist is Swagata Adhikary, also one the first co-author of the paper.
Playing origami with DNA to see what happens next
This article highlights research in the paper by one of the finalists of the Inspiring Science Awards 2025. The finalist is Shuvra Shekhar Roy, also the first author of the paper.
Predict, err, update: Lessons from larval zebrafish
This article highlights research in the paper by one of the finalists of the Inspiring Science Awards 2025. The finalist is Sriram Narayanan, also the first author of the paper.
When cells fire one DNA handyman to hire another
This article highlights research in the paper by one of the finalists of the Inspiring Science Awards 2025. The finalist is Srijita Paul Chowdhuri, also the first author of the paper.
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